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Milan to Palermo by train
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Cheapest Price £5.31
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30 days in advance £178.02
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First train19:05
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Last train20:10
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Avg changes0
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Fastest journey20hr 29m
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Distance886 kilometres
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Trains per day2
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Avg. journey time21hr 35m
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Train operators
Milan to Palermo train travel explained
Want to know how to get from Milan to Palermo by train? We have gathered for you all the useful information about this trip!
The fastest trains from Milan to Palermo take around 20 hours and 29 minutes, covering a distance of approximately 886 kilometres.
On weekdays the only train to Palermo is usually scheduled to depart Milan around . This is the same as during the weekend. On average, there are about 2 trains per day travelling between the two cities. They leave approximately every 55 minutes.
Prices for a single ticket between the two cities start from £5.32.
We think any time is a great time to visit Palermo, as each season has its own unique charm. Nevertheless, please make sure you check the local weather and average seasonal temperatures at destination before deciding on your holiday.
For more tips to help you plan your journey, check out our help articles, or read our guide to Palermo.
Is there a direct train from Milan to Palermo?
Yes, there is a direct train from Milan to Palermo.
How long does it take to travel from Milan to Palermo?
The Milan to Palermo train travel takes about 20 hours and 29 minutes, no matter when you leave.
What are the Milan to Palermo train times and schedule?
On weekdays the only train to Palermo is usually scheduled to depart Milan around . This is the same at the weekend.
Other journeys to Palermo View all journeys to Palermo
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From Naples to Palermo From £2.73
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From Catania to Palermo From £15.12
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From Messina to Palermo From £5.38
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From Cefalù to Palermo From £6.42
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From Rome to Palermo From £5.38
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From Agrigento Centrale to Palermo From £7.80
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From Piraineto to Palermo From £4.28
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From Taormina-Giardini to Palermo From £16.08
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From Syracuse to Palermo From £17.92
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From London to Palermo From £65.56
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From Paris to Palermo From £33.48
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From Trapani to Palermo From £12.30
Other journeys from Palermo
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From Palermo to Naples From £2.65
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From Palermo to Catania From £15.49
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From Palermo to Piraineto From £4.28
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From Palermo to Cefalù From £6.42
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From Palermo to Agrigento Centrale From £9.70
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From Palermo to Rome From £5.38
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From Palermo to Taormina-Giardini From £7.67
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From Palermo to Trapani From £11.90
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From Palermo to Syracuse From £14.75
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From Palermo to Campofelice From £10.62
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From Palermo to Patti-S. Piero Patti From £11.28
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From Palermo to Capo d'Orlando-Naso From £10.10
Other journeys from Milan
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From Milan to Florence From £2.65
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From Milan to Pisa From £2.65
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From Milan to Venice From £9.00
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From Milan to Rome From £2.73
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From Milan to Verona From £8.78
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From Milan to Taormina-Giardini From £110.47
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From Milan to Padua From £8.85
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From Milan to Bari From £2.73
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From Milan to Bergamo From £7.67
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From Milan to Trieste Centrale From £11.43
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From Milan to Como From £4.57
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From Milan to Marseille From £5.38
Intercity Notte night train
The overnight train from Milan to Sicily is an excellent option for reaching Palermo. The train also conveys sleeping cars and couchettes from Milan direct to other towns in Sicily: Cefalù, Catania, Taormina and Syracuse.
The night train from Milan to Palermo first runs south to the coast at Genoa. It then broadly follows the west coast for the entire length of Italy down to Villa San Giovanni where the train is shipped onto a ferry for the short sea crossing to Sicily.
If you don’t like the idea of a long overnight journey, it is also possible to travel by day from Milan to Palermo, usually with just one change of train along the way. Take a morning high-speed train from Milan to either Naples or Salerno, transferring at one of these stations to an onward Intercity train to Sicily.
Milan Centrale to Palermo Centrale (night train)

The night train to Sicily departs from Milano Centrale. You have a choice of either couchette or sleeping car accommodation on this Intercity Notte service. The latter is more comfortable and thus the better choice for the long journey to Palermo.
This train stops during the evening at a number of places along the Ligurian and Tuscan coast to pick up passengers. These stops include Genoa, Pisa and Livorno. The train then runs non-stop for some hours to allow passengers to sleep. By the following morning, you’ll be running down the coast of Calabria as the train heads for the ferry to Sicily. The train slips on board the ferry and within an hour you are in Sicily. The train then tracks west along Sicily's north coast to reach Palermo Centrale.