St Louis to Florence by train
Compare prices, times and book fast direct trains
Overview: trains from St Louis to Florence
Find the key information for travelling by train from St Louis to Florence, including journey times, fares and operators serving the route. Compare your options and plan the journey that works for you with Rail Europe.
Travelling from St Louis to Florence by train
Want to know how to get from St Louis to Florence by train? We have gathered for you all the useful information about this trip!
The fastest trains from St Louis to Florence take around 7 hours and 22 minutes, covering a distance of approximately 513 kilometres.
On weekdays, the first train leaving St Louis is scheduled to depart at around 10:14. The last departure is usually at around 19:12 . On Saturdays and Sundays, trains leave St Louis at around 06:42, with the last train leaving at around 21:35. On average, there are about 6 trains per day travelling between the two cities. They leave approximately every 1 hour and 42 minutes.
Prices for a single ticket between the two cities start from US$153.60.
We think any time is a great time to visit Florence, as each season has its own unique charm. Nevertheless, please make sure you check the local weather and average seasonal temperatures at destination before deciding on your holiday.
For more tips to help you plan your journey, check out our help articles, or read our guide to Florence.
Is there a direct train from St Louis to Florence?
The journey between St Louis and Florence usually involves changes of train.
We usually find around departures on this route every weekday, counting only those that leave enough time to change trains without waiting around for longer than necessary.
Trains are typically more frequent on weekends, when we found around departures.
How long does it take to travel from St Louis to Florence?
The St Louis to Florence train travel takes about 7 hours and 22 minutes, no matter when you leave.
What are the St Louis to Florence train times and schedule?
If you're travelling on a weekday, you'll find the earliest train to Florence leaving St Louis at around 10:14 and the last train leaving at around 19:12 . At weekends, the first train of the day leaves St Louis at around 06:42, with the final departure at 21:35.
Other train journeys from St Louis
- From St Louis to Mulhouse From US$5.00
- From St Louis to Colmar From US$7.50
- From St Louis to Strasbourg From US$13.00
- From St Louis to Basel From US$4.00
- From St Louis to Lucerne From US$28.50
- From St Louis to Freiburg From US$28.50
- From St Louis to Sélestat From US$24.00
- From St Louis to Bern From US$38.50
- From St Louis to Interlaken From US$53.00
- From St Louis to Zurich From US$33.00
- From St Louis to Paris From US$67.00
- From St Louis to Besançon From US$40.50
- From St Louis to Dijon From US$39.50
- From St Louis to Milan From US$93.50
- From St Louis to Belfort From US$22.50
Other train journeys to Florence
- From London to Florence From US$199.80
- From Paris to Florence From US$84.00
- From Milan to Florence From US$7.00
- From Rome to Florence From US$15.20
- From Venice to Florence From US$42.70
- From Verona to Florence From US$12.00
- From Genoa to Florence From US$7.00
- From Cannes to Florence From US$58.30
- From Ventimiglia to Florence From US$35.20
- From Bologna to Florence From US$11.70
- From Turin to Florence From US$15.10
- From Nice to Florence From US$7.00
- From Padua to Florence From US$17.00
- From Viareggio to Florence From US$13.40
- From Montecatini Terme to Florence From US$15.70
Other train journeys from Florence
- From Florence to Milan From US$7.00
- From Florence to Rome From US$3.50
- From Florence to Venice From US$16.20
- From Florence to Perugia From US$38.40
- From Florence to Siena From US$12.90
- From Florence to Verona From US$12.00
- From Florence to Pisa From US$11.40
- From Florence to La Spezia From US$15.00
- From Florence to Naples From US$15.20
- From Florence to Lucca From US$10.30
- From Florence to Arezzo From US$3.50
- From Florence to Livorno From US$13.30
230+ European rail operators Official partner of 230+ European rail operators
Travellers rate us "Excellent!"
Blog posts featuring St Louis or Florence
-
Italy in 2025: What to see, where to go and the high-speed train that gets you there!
Italy is always a good idea, but in 2025, with once-in-a-century festivals and promising travel trends, it’s more tempting than ever! Read more
-
The best trains from Paris for exploring France and the rest of Europe
So, you’ve done Paris and you need a little bit more European excitement, a more sedate city perhaps, one that has mountains not just museums, or vineyards and valleys rather than Versailles.Read more
-
20% Off Global & One Country Eurail and Interrail Passes!
Plus 20 tips to make the most out of your Pass! Read more