Travelling from Rome to Mendrisio by train

Want to know how to get from Rome to Mendrisio by train? We have gathered for you all the useful information about this trip!

The fastest trains from Rome to Mendrisio take around 4 hours and 18 minutes, covering a distance of approximately 523 kilometres.

On weekdays, the first train leaving Rome is scheduled to depart at around  00:11. The last departure is usually at around 23:55 . On Saturdays and Sundays, trains leave Rome at around 00:11, with the last train leaving at around 23:00. There are frequent services on this particular rail route. On average, there are about 19 trains per day travelling between the two cities. They leave approximately every 25 minutes.

Prices for a single ticket between the two cities start from US$71.60.

We think any time is a great time to visit Mendrisio, as each season has its own unique charm. Nevertheless, please make sure you check the local weather and average seasonal temperatures at destination before deciding on your holiday.

For more tips to help you plan your journey, check out our help articles, or read our guide to Mendrisio.

Is there a direct train from Rome to Mendrisio?

The journey between Rome and Mendrisio usually involves changes of train.

We usually find around departures on this route every weekday, counting only those that leave enough time to change trains without waiting around for longer than necessary.

There are typically fewer trains leaving at weekends, when we found around departures.

How long does it take to travel from Rome to Mendrisio?

The Rome to Mendrisio train travel takes about 4 hours and 18 minutes, no matter when you leave.

What are the Rome to Mendrisio train times and schedule?

If you're travelling on a weekday, you'll find the earliest train to Mendrisio leaving Rome at around 00:11 and the last train leaving at around 23:55 . At weekends, the first train of the day leaves Rome at around 00:11, with the final departure at 23:00.