Prague to Mainz train travel explained

Want to know how to get from Prague to Mainz by train? We have gathered for you all the useful information about this trip!

The fastest trains from Prague to Mainz take around 7 hours and 32 minutes, covering a distance of approximately 443 kilometres.

On weekdays, the first train leaving Prague is scheduled to depart at around  03:08. The last departure is usually at around 23:26 . On Saturdays and Sundays, trains leave Prague at around 03:08, with the last train leaving at around 23:50. There are frequent services on this particular rail route. On average, there are about 49 trains per day travelling between the two cities. They leave approximately every 6 minutes.

Prices for a single ticket between the two cities start from US$53.50.

We think any time is a great time to visit Mainz, as each season has its own unique charm. Nevertheless, please make sure you check the local weather and average seasonal temperatures at destination before deciding on your holiday.

For more tips to help you plan your journey, check out our help articles, or read our guide to Mainz.

Is there a direct train from Prague to Mainz?

The journey between Prague and Mainz usually involves one change of train.

We usually find at least one departure on the route from Prague to Mainz every weekday that leave enough time to change trains without waiting around for longer than necessary.

Trains are typically more frequent on weekends, when we found at least one departure.

How long does it take to travel from Prague to Mainz?

The Prague to Mainz train travel takes about 7 hours and 32 minutes, no matter when you leave.

What are the Prague to Mainz train times and schedule?

If you're travelling on a weekday, you'll find the earliest train to Mainz leaving Prague at around 03:08 and the last train leaving at around 23:26 . At weekends, the first train of the day leaves Prague at around 03:08, with the final departure at 23:50.