Mainz to Prague train travel explained

Want to know how to get from Mainz to Prague by train? We have gathered for you all the useful information about this trip!

The fastest trains from Mainz to Prague take around 7 hours and 35 minutes, covering a distance of approximately 443 kilometres.

On weekdays, the first train leaving Mainz is scheduled to depart at around  00:29. The last departure is usually at around 23:54 . On Saturdays and Sundays, trains leave Mainz at around 00:41, with the last train leaving at around 23:54. There are frequent services on this particular rail route. On average, there are about 43 trains per day travelling between the two cities. They leave approximately every 16 minutes.

Prices for a single ticket between the two cities start from US$46.50.

We think any time is a great time to visit Prague, as each season has its own unique charm. Nevertheless, please make sure you check the local weather and average seasonal temperatures at destination before deciding on your holiday.

For more tips to help you plan your journey, check out our help articles, or read our guide to Prague.

Is there a direct train from Mainz to Prague?

The journey between Mainz and Prague usually involves one change of train.

We usually find at least one departure on the route from Mainz to Prague every weekday that leave enough time to change trains without waiting around for longer than necessary.

Trains are typically more frequent on weekends, when we found at least one departure.

How long does it take to travel from Mainz to Prague?

The Mainz to Prague train travel takes about 7 hours and 35 minutes, no matter when you leave.

What are the Mainz to Prague train times and schedule?

If you're travelling on a weekday, you'll find the earliest train to Prague leaving Mainz at around 00:29 and the last train leaving at around 23:54 . At weekends, the first train of the day leaves Mainz at around 00:41, with the final departure at 23:54.